Role of Psychological Effects on Treatment of Vitiligo in Adolescent Patients in Alsahl Algharbiu Area

المؤلفون

  • Sana Mohamed Dhou Al-Hanashi University of Sabratha – Libya/ Faculty of Pharmacy/ Department of Biomedical Sciences المؤلف

DOI:

https://doi.org/10.65405/gtha0867

الكلمات المفتاحية:

Vitiligo; Adolescents; Psychological factors; Anxiety; Depression; Treatment outcome

الملخص

Background: Vitiligo is a chronic depigmenting disorder associated with significant psychologicalburden, particularly among adolescents.

Objective: To evaluate the impact of psychological factors on treatment outcomes in adolescentpatients with vitiligo.

Methods: A cross-sectional analytical study was conducted on 60 adolescents aged 12–18 years.Psychological status was assessed using validated measures of anxiety, depression, and self-esteem.Treatment response was clinically evaluated. Statistical analysis was performed using SPSS version 26.

Results: Anxiety and depression showed significant negative correlations with treatment response (r =−0.48, p = 0.001; r = −0.52, p < 0.001). Self-esteem demonstrated a positive correlation (r = 0.45, p =0.002). Regression analysis identified depression as the strongest predictor.

Conclusion: Psychological factors significantly influence treatment outcomes in adolescent vitiligopatients. Integrating psychological care may improve therapeutic outcomes.

التنزيلات

تنزيل البيانات ليس متاحًا بعد.

المراجع

1. Taieb A, Picardo M. Clinical practice. Vitiligo. N Engl J Med. 2009;360(2):160–169.

2. Ezzedine K, Eleftheriadou V, Whitton M, van Geel N. Vitiligo. Lancet. 2015;386(9988):74–84.

3. Silverberg JI, Silverberg NB. Association between vitiligo extent and quality of life impairment. JAMA Dermatol. 2013;149(2):159–164.

4. Ongenae K, Van Geel N, De Schepper S, Naeyaert JM. Psychosocial effects of vitiligo. J Eur Acad Dermatol Venereol. 2006;20(1):1–8.

5. Porter JR, Beuf AH, Nordlund JJ, Lerner AB. Psychological reaction to chronic skin disorders: a study of patients with vitiligo. Gen Hosp Psychiatry. 1979;1(1):73–77.

6. Kent G, Al-Abadie M. Psychologic effects of vitiligo: a critical incident analysis. J Am Acad Dermatol. 1996;35(6):895–898.

7. Parsad D, Dogra S, Kanwar AJ. Quality of life in patients with vitiligo. Health Qual Life Outcomes. 2003;1:58.

8. Sampogna F, Tabolli S, Abeni D. Living with vitiligo: impact on quality of life. Br J Dermatol. 2005;152(5):1003–1008.

9. Schallreuter KU, Salem MA, Gibbons NCJ, Rokos H, Wood JM. Stress and vitiligo: neuroendocrine pathways. Exp Dermatol. 2012;21(1):37–42.

10. Picardi A, Pasquini P, Cattaruzza MS, et al. Stressful life events and vitiligo. Psychother Psychosom. 2003;72(3):150–158.

11. Papadopoulos L, Bor R, Legg C. Coping with vitiligo: CBT approach. Br J Med Psychol. 1999;72(3):385–396.

12. Hamidizadeh N, Ranjbar S, Ghanizadeh A. Anxiety and depression in adolescents with vitiligo. J Dermatol Treat. 2016;27(2):172–175.

13. Ezzedine K, Whitton M, Pinart M, et al. Interventions for vitiligo. Cochrane Database Syst Rev. 2016;CD003263.

14. Agila, F. E. S. (2026). Insecticidal effectiveness of seed and leaf oil extract of neem (Azadirachta indica) against larvae and adults of Anopheles stephensi. Al-Farooq Journal of Sciences, 2(3), 429-441.

15. Alboueishi, F. A. A. (2026). Efficacy of Curcumin on Inflammatory Biomarkers in Type 2 Diabetes: A Meta-Analysis of Clinical Trials and Animal Studies Systematic Review & Meta-Analysis (PRISMA 2020) Field: Botany & Complementary Medicine. Al-Farooq Journal of Sciences, 2(2), 15-35.

16. Bergqvist C, Ezzedine K. Vitiligo: pathogenesis and management. Dermatol Clin. 2020;38(1):1–10.

17. Hamron, A. M., Barakat, A. H., Qaed, H. M., & Emran, F. (2026). Evaluation of the antifungal efficacy of Salvia officinalis extract against some clinical oral candidiasis isolates: a comparative study with standard antifungals. Al-Farooq Journal of Sciences, 2(1), 1242-1252.

18. Seneschal J, Boniface K, D'Arino A, Picardo M. Immune mechanisms in vitiligo. Nat Rev Immunol. 2021;21(5):321–333.

19. Alikhan A, Felsten LM, Daly M, Petronic-Rosic V. Vitiligo: review of pathogenesis and treatment. J Am Acad Dermatol. 2011;65(3):473–491.

20. Rodrigues M, Ezzedine K, Hamzavi I, Pandya AG, Harris JE. Vitiligo working group recommendations. JAMA Dermatol. 2017;153(7):666–674

التنزيلات

منشور

2026-06-30

كيفية الاقتباس

Role of Psychological Effects on Treatment of Vitiligo in Adolescent Patients in Alsahl Algharbiu Area. (2026). مجلة العلوم الشاملة, 11(41), 1758-1767. https://doi.org/10.65405/gtha0867