Studying the effect of ultraviolet C radiation on the fine structure of rat skin tissue and blood analysis using transmission electron microscopy

Authors

  • Sumaya Alusta Department of Physics to divide Physiotherapy, Faculty of Health Sciences/Al-Ajilat, University of Zawia, Libya Author
  • Maryem Badra Department of Physics, Faculty of Sciences/Al-Ajilat, University of Zawia, Libya Author
  • Salah Alsokni Department of Microbiology to divide Laboratories, Faculty of Health Sciences/Al-Ajilat, University of Zawia, Libya Author

DOI:

https://doi.org/10.65405/der4bt20

Keywords:

Ultraviolet C radiation, Rat skin, Ultrastructural microscopy, Transmission electron microscopy, Blood analysis

Abstract

This study aimed to evaluate the ultraviolet-C (UVC) effects of radiation on the skin of Wistar rats and its impact on blood parameters. Forty adult rats were used, divided into a control group and three experimental groups exposed to artificial UVC (254 nm) radiation for 8, 16, and 24 days, 8 hours per day. Transmission electron microscopy results showed progressive damage to skin cells with increasing exposure time, including: nuclear envelope irregularities, mitochondrial swelling, increased melanin granule accumulation, keratinocyte and collagen filament disruption, and widening of cell junctions. In addition, blood analysis revealed significant changes in blood parameters: decreased hemoglobin and red blood cell (RBC) levels with longer exposure, as well as changes in white blood cell (WBC) levels, with statistical significance at p < 0.05. These results confirm the harmful effects of UVC radiation on the skin and blood, and reflect the relationship between exposure duration and biological changes, highlighting the importance of taking precautionary measures when using UVC radiation industrially.

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References

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Published

2026-03-01

Issue

Vol. 10 No. 39 (2026): Comprehensive Journal of Science

Section

المقالات

License

Copyright (c) 2026 Comprehensive Journal of Science

Creative Commons License

This work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License.

How to Cite

Studying the effect of ultraviolet C radiation on the fine structure of rat skin tissue and blood analysis using transmission electron microscopy. (2026). Comprehensive Journal of Science, 10(39), 3977-3986. https://doi.org/10.65405/der4bt20